Educational reference/not medical advice/consult a clinician
SP Speak PeptidesPeptide Library
2026 Edition · Updated regularly

Peptides are signals between cells. Here's the field guide.

The complete guide to peptides. What they are, what they do, who they're for — in plain language, not textbook.

Athletic woman runner in motion Reference · 2026 Edition
compounds
In the index
categories
Sorted by use
steps
How they work
tools
Decide where to start
Protein fibers under high magnification
Reference · 01
01 — Overview

What is a peptide?

Think of your body as a city full of cells, all talking to each other constantly. Peptides are the text messages. Short, specific, fast. They tell cells when to grow, when to repair, when to release a hormone, when to feel hungry, when to feel full.

Key Idea
Peptides aren't fuel. They're instructions. Small messages that tell your body what to do.

Your body already makes thousands of peptides on its own. The ones in this catalogue are lab-made versions of those natural signals. Some copy a signal exactly. Others last longer or bind more strongly. They're powerful, and worth taking seriously.

02 — Mechanism

How they work.

Visual · How binding works

Peptide-Receptor Binding

A peptide arrives, finds its receptor, locks in, and triggers a response inside the cell.

01 Peptide
02 Receptor
03 Binding
04 Biological
Response
Step 01

Get into the body

Most peptides can't survive stomach acid. So they're delivered as a shot, a nasal spray, or a cream. Digestion gets skipped entirely.

Step 02

Find their target

Each peptide is built to dock onto a specific spot on a specific cell. A key fitting one lock. Weight-loss peptides find appetite cells. Healing peptides find injured tissue.

Step 03

Send the message

Once docked, the peptide tells the cell what to do. Release a hormone. Slow digestion. Build new tissue. Calm inflammation. The cell follows the instruction.

Step 04

Get cleared out

The body breaks them down quickly. Minutes to hours. How fast they clear is what sets the dosing schedule. Some are engineered to last days.

03 — Use Cases

What peptides are used for.

Every peptide here falls into one of six groups, sorted by what it actually does. Tap a category to jump to those entries in the index.

05 — The Reference

All 25 peptides, in one place.

Searchable, filterable, with full breakdowns for each. What it is. How it works. What it's used for. Below — the four most-searched, as a starting point.

Want to see them all? Browse the full catalogue
The telehealth landscape · 2026

How most people actually access peptides today.

Three years ago, peptide access meant convincing a primary-care doctor to write a prescription, or buying gray-market vials online. Today the dominant path is telehealth — and the category has fragmented into three distinct lanes worth understanding before you pick one.

$58B
Global GLP-1 market 2026
The fastest-growing prescription drug category of the decade.
~10M
Americans on GLP-1s
Up from 5M in 2023. Projected to reach 25M by 2030.
$349/mo
Lowest legitimate cash-pay
NovoCare's direct-to-consumer Wegovy price (2025).
Three lanes · what to look for · red flags Read the full guide
Editorial · Long reads

Deep dives.

In-depth comparisons and analyses on the most-searched questions about peptides — sourced, currently dated, and built to be the page you forward to a friend.

Patient guide · 10 min read

What to actually ask your doctor about Ozempic, Wegovy, or Zepbound

The 9 questions most patients don't think to ask before starting a GLP-1 — and what the right answers sound like. Built to bring to the appointment.

Read the checklist
Industry · 2026 · 13 min read

The peptide telehealth landscape in 2026

Three years ago, peptide access meant a primary-care prescription or gray-market vials online. Today, telehealth is the default — fragmented into three recognizable lanes with very different economics and clinical depth. Here's the field guide.

Read the guide
Healing comparison · 11 min read

BPC-157 vs TB-500 — what the evidence actually shows

The two most-searched recovery peptides on the consumer internet. Both have extensive animal research. Both have almost no published human clinical trials. Here's what the science actually says — and what gym forums get wrong about both.

Read the comparison
Regulatory · 2026 · 11 min read

Is compounded GLP-1 still legal in 2026?

The FDA shortage exception that legalized compounded Ozempic and Mounjaro ended in 2025. As of April 30 2026, the FDA has formally proposed permanently closing the door — for both 503A pharmacies and 503B outsourcing facilities. So why are clinics still selling it?

Read the analysis
GLP-1 comparison · 12 min read

Tirzepatide vs Semaglutide vs Retatrutide

The three biggest weight-loss drugs of the 2020s pull different sets of metabolic levers — one, two, and three respectively. The differences in the trial data are larger than most articles will tell you. Here's the comparison, sourced and current.

Read the comparison
Decide where to start

Two tools. One question: where do you start?

New to this or already mixing your first vial. Both answers live behind one of these buttons.

04 — Administration

How they're used.

A quick orientation. Most peptides ship as vials and follow the syringe routine. A few come as pre-filled pens — easier, but only available for select compounds.

  1. 01

    What you'll need

    The vial of peptide. Bacteriostatic water. Insulin syringes. Alcohol swabs. A sharps container for safe disposal.

  2. 02

    Mix it

    Pull bacteriostatic water into a syringe. Slowly inject it into the vial along the side. Swirl gently. Don't shake. The powder dissolves.

  3. 03

    Draw your dose

    Pull the calculated amount into a clean insulin syringe. Tap to bring air bubbles to the top. Push them out before injecting.

  4. 04

    Inject it

    Most peptides are subcutaneous — into the soft fat of the belly or thigh. Clean the spot. Pinch the skin. Insert at 90°. Push slowly. Withdraw.

  5. 05

    Store it

    Reconstituted vials go in the fridge. Use within 30 days. Drop used syringes into a sharps container — never in regular trash.

Alternative · for some peptides

Or skip the routine — use a pen.

A growing number of peptides now ship as pre-filled, pre-dosed pens. Click a dial. Press a button. The reconstitution-and-syringe routine — gone, for these.

Live demo · auto-loop Dialing dose…
0.0 mg
  1. 01 Dial the dose
  2. 02 Press to skin
  3. 03 Click. Hold. Done.
Available in pen form

What you can get pre-loaded

SemaglutideOzempic, Wegovy TirzepatideMounjaro, Zepbound LiraglutideSaxenda, Victoza HGHNorditropin, Genotropin TeriparatideForteo
+

Easier. No mixing, no math, no syringe handling. Significantly lower barrier to consistent dosing.

+

Safer. Pre-measured doses eliminate calculation errors. The needle is built in, sterile, and shielded.

Pricier. Convenience costs more per dose than vials — often substantially more.

Limited menu. Only some peptides come in pen form. Most research peptides still ship as vials.

Risks worth knowing
  • Sterility. Research-grade vials aren't made to USP <797> standards. Bacterial contamination is the most realistic acute harm. If a reconstituted vial looks cloudy or has particulates, do not use it.
  • Bac water shelf life. After first puncture, bacteriostatic water is good for ~28 days. Older bac water can grow microbes despite the benzyl alcohol preservative.
  • Anaphylaxis. Rare with peptides but possible with any injectable. Don't dose alone the first time. Know the signs — hives, swelling, difficulty breathing — and have a plan.
  • Needle hygiene. One needle per injection. Never share needles or syringes — that's how hep B, hep C and HIV move between people.
  • Injection-site infection. Spreading redness, fever, warmth, or red streaking from the site is a call-the-doctor situation, not a wait-and-see one.
  • Sourcing. Two vials with the same label can have very different actual contents. Reputable third-party purity testing (HPLC + mass spec certificates of analysis) is the bare minimum.

This is general orientation, not medical instruction. Specific peptides have specific protocols. Always work with a doctor who knows what you're using.

06 — Common questions

Things people ask first.

Quick answers to the questions that come up most. The full reference covers each peptide in more depth.

What's the difference between research-grade and prescription peptides?

Prescription peptides like Ozempic or Wegovy are FDA-approved drugs. You get them from a pharmacy with a doctor's prescription. They've been through clinical trials. They're produced under strict pharmaceutical standards. They're legal to use as prescribed.

Research-grade peptides are sold "for research purposes only." Meaning produced for laboratory use, not human use. They're widely available online but exist in a legal gray area. Quality varies significantly between sources.

Are peptides legal?

It depends on which one and how you're getting it. FDA-approved peptides through a licensed prescriber and pharmacy are fully legal. Research-grade peptides sit in a gray zone. They're sold legally for research use. Using them on yourself is technically off-label and unregulated.

The FDA's compounding policy on peptides has been moving fast. In April 2026 the FDA removed twelve peptides — including BPC-157, TB-500, GHK-Cu (injectable), MT-2, KPV, MOTS-c, DSIP, Epitalon and Semax — from Category 2 of the interim 503A bulks list. CJC-1295 was removed earlier (September 2024). Removal does not mean approval. The Pharmacy Compounding Advisory Committee (PCAC) is reviewing these substances starting July 2026 and will recommend whether each can be added to the 503A Bulks List for compounding. PCAC has previously voted against CJC-1295, ipamorelin, and thymosin alpha-1.

Last reviewed: May 18, 2026. Each peptide entry has its own regulatory status.

How is this different from steroids?

Steroids are synthetic versions of hormones, mostly testosterone. Peptides are short chains of amino acids that act as signaling molecules. They tell your body what to do. They don't replace a hormone directly.

A growth hormone peptide like Sermorelin tells your pituitary to release more of your own growth hormone. Direct HGH injections are synthetic hormone replacement. Different mechanism. Different risk profile. Different legal status.

Do I need a doctor to use peptides?

For prescription peptides, yes. You'll need a doctor or telehealth provider to write the prescription. Many telehealth services now specialize in peptides.

For research-grade peptides, no doctor is involved in the purchase. But that doesn't mean a doctor isn't a good idea. Working with someone who knows your bloodwork and medical history is the difference between informed experimentation and gambling with your body.

How do I know which peptide is right for me?

Start with the goal, not the compound. Body composition? Recovery from injury? Sleep? Focus? Skin? Each goal has a small set of peptides associated with it.

The Find your match tool walks you through 5 questions and recommends peptides matched to your goal and comfort level. Or browse the full catalog sorted by category.

What does "reconstitution" mean?

Most research-grade peptides ship as a freeze-dried powder in a vial. Before you can use them, you mix the powder with bacteriostatic water. That turns it into a liquid you can draw into a syringe. The mixing step is called reconstitution.

Getting the math right matters. Too much water and your dose is too dilute. Too little and you can't draw it accurately. The built-in calculator does the math for you.

07 — Important

Read this before going further.

  1. This isn't medical advice.

    Everything on this site is for learning, not for treating yourself. Nothing here is a recommendation to use, buy, or inject any of these peptides. Real health decisions belong with a doctor who knows your full picture.

  2. Most of these aren't supplements.

    Most peptides aren't regulated like vitamins or supplements. Many are prescription-only drugs. Some are still being tested. Some are sold only for lab research. Treating them like a casual wellness purchase is a mistake.

  3. Where you buy from matters.

    Compounds sold "for research only" don't follow the same manufacturing standards as actual medications. Two vials with the same label can have very different actual contents. Quality, purity, and what's actually in there varies a lot between sources.

  4. The science isn't finished.

    For a lot of these peptides, we don't yet know what years or decades of regular use does to a person. Animal studies and a few months of human trials can't tell us about long-term safety.

  5. Talk to a real doctor.

    If something on this site interests you, the next step is a conversation with a doctor. Ideally one who knows hormones, metabolic medicine, or the specific peptide you're curious about. Not a forum. Not an influencer. Not a guy at the gym.

  6. How this reference is maintained.

    Every entry shows a last reviewed date. Regulatory status is checked against the FDA Bulk Drug Substances list, FDA approval letters and PCAC meeting minutes. Clinical claims should be reviewed by a named medical reviewer before broader release — this v1 is the editorial pass. If you find an error, please write us; corrections are logged with a date.